* denotes equal contributions

J. Shida*, K. Ma*, H. Toll*, O. Salinas*, X. Ma, C.S. Peng. Multicolor Long-Term Single-Particle Tracking Using 10 nm Upconverting Nanoparticles. Nano Letters 24, 14, 4194-4201 (2024) [link]

C. S. Peng, Y Zhang, Q. Liu, G.E. Marti, Y-W. A. Huang, T.C. Südhof, B. Cui, S. Chu. Nanometer-Resolution Real-Time Tracking of Single Cargos During Axonal Transport by Dynein. bioRxiv 2022.01.05.475120 [link]

C. A. McLellan, C. Siefe, J. Casar, C. S. Peng, S. Fischer, A. Lay, A. Parakh, F. Ke, X. W. Gu, W. Mao, S. Chu, M. B. Goodman, J. A. Dionne, Engineering bright and mechanosensitive alkaline-earth rare-earth upconverting nanoparticles. J. Phys. Chem. Lett. 13, 1547-1553 (2022). [link]

C. Siefe, R. D. Mehlenbacher, C. S. Peng, Y. Zhang, S. Fischer, A. Lay, C. A. McLellan, A. P. Alivisatos, S. Chu, and J. A. Dionne. Sub-20 nm Core–Shell–Shell Nanoparticles for Bright Upconversion and Enhanced Förster Resonant Energy Transfer. J. Am. Chem. Soc.  141, 42, 16997-17005 (2019). [link]

Q. Liu*, Y Zhang*, C. S. Peng*, T. Yang, L-M. Joubert, and S. Chu. Single upconversion nanoparticle imaging at sub-10 W/cm2 irradiance. Nature Photonics 12, 548-553 (2018). [link | Stanford Medicine News]

R. A. Coleman, Z. Qiao, S. K. Singh, C. S. Peng, M. Cianfrocco, Z. Zhang, A. Piasecka, H. Aldeborgh, G. Basishvili and W. L. Liu. p53 dynamically directs TFIID assembly on target gene promoters. Mol. Cell. Biol. 37, e00085-17 (2017). [link]

XX. Zhang, K. C. Jones, A. Fitzpatrick, C. S. Peng, CJ Feng, C. R. Baiz, A. Tokmakoff. Studying Protein-Protein Binding through T-Jump Induced Dissociation: Transient 2D IR Spectroscopy of Insulin Dimer. J. Phys. Chem. B 120, 5134-5145 (2016). [link]

Q. Dai*, P. J. Sanstead*, C. S. Peng*, D. Han, C. He, and A. Tokmakoff. Weakened N3 hydrogen bonding by 5-formylcytosine and 5-carboxylcytosine reduces their base-pairing stability. ACS Chem. Biol. 11, 470 (2016). [link]

C. S. Peng*, B. I. Fedeles*, V. Singh, D. Li, T. Amariuta, J. M. Essigmann, and A. Tokmakoff. Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity. Proc. Natl. Acad. Sci. U.S.A. 112, 3229-34 (2015). [link | University of Chicago News] 

D. Li*, B. I. Fedeles*, V. Singh*, C. S. Peng*, K. J. Silvestre, A. K. Simi, J. H. Simpson, A. Tokmakoff, and J. M. Essigmann. Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside analog 5-aza-5,6-dihydro-2'-deoxycytidine. Proc. Natl. Acad. Sci. U.S.A. 111, E3252-E3259 (2014). [link | MIT News]

C. R. Baiz, Y.-S. Lin, C. S. Peng, K. A. Beauchamp, V. A. Voelz, V. S. Pande, and A. Tokmakoff. A molecular interpretation of 2D IR protein folding experiments with Markov State Models. Biophys. J. 106, 1359-1370 (2014). [link]

V. Singh, C. S. Peng, D. Li, K. Mitra, K. J. Silvestre, A. Tokmakoff, and J. M. Essigmann. Direct observation of multiple tautomers of oxythiamine and their recognition by the thiamine pyrophosphate riboswitch. ACS Chem. Biol. 9, 227-236 (2013). [link]

C. S. Peng, C. R. Baiz, and A. Tokmakoff. Direct observation of ground-state lactam–lactim tautomerization using temperature-jump transient 2D IR spectroscopy. Proc. Natl. Acad. Sci. U.S.A. 110, 9243-9248 (2013). [link]

K. C. Jones, C. S. Peng, and A. Tokmakoff. Folding of a heterogeneous beta-hairpin peptide from temperature-jump 2D IR spectroscopy. Proc. Natl. Acad. Sci. U.S.A. 110, 2828-2833 (2013). [link]

C. S. Peng and A. Tokmakoff. Identification of lactam–lactim tautomers of aromatic heterocycles in aqueous solution using 2D IR spectroscopy. J. Phys. Chem. Lett. 3, 3302-3306 (2012). [link]

K. C. Jones, Z. Ganim, C. S. Peng, and A. Tokmakoff. Transient two-dimensional spectroscopy with linear absorption corrections applied to temperature-jump two-dimensional infrared. J. Opt. Soc. Am. B 29, 118-129 (2012). [link]

C. R. Baiz, C. S. Peng, M. E. Reppert, K. C. Jones, and A. Tokmakoff. Coherent two-dimensional infrared spectroscopy: quantitative analysis of protein secondary structure in solution. Analyst 137, 1793-9 (2012). [link | MIT News]

C. S. Peng, K. C. Jones, and A. Tokmakoff. Anharmonic vibrational modes of nucleic acid bases revealed by 2D IR spectroscopy. J. Am. Chem. Soc. 133, 15650-15660 (2011). [link]

A. W. Smith, J. Lessing, Z. Ganim, C. S. Peng, A. Tokmakoff, S. Roy, T. L. C. Jansen, and J. Knoester. Melting of a beta-hairpin peptide using isotope-edited 2D IR spectroscopy and simulations. J. Phys. Chem. B 114, 10913-10924 (2010). [link]

O. Kornilov, C. C. Wang, O. Bunermann, A. T. Healy, M. Leonard, C. Peng, S. R. Leone, D. M. Neumark, and O. Gessner. Ultrafast dynamics in Helium nanodroplets probed by femtosecond time-resolved EUV photoelectron imaging. J. Phys. Chem. A 114, 1437-1445 (2010). [link]